Studied painting, sculpture and color theory at The Cooper Union. During this period, she created electronic multi-track compositions and studied and performed West African (Senegalese) dance (11 years).

Nisi’s video pieces were presented in programs at the Jeu De Paume Museum, Paris, River to River Film Festival, Tribeca Film Festival, Hong Kong Film Festival, Circulo de Bellas Artes of Madrid, Maya Stendhal Gallery, SONAR festival at the Caracas Contemporary Art Museum, CalArts Film/Video Cinematheque, Haus der Kulturen der Welt in Berlin, The Alejandro Otero Museum, National Cinématheque of Spain, Manchester Metropolitan University of England.

From 2007-2011, DRAW was a collaboration between Michael J. Schumacher and Nisi Jacobs; exhibited multichannel sound/video immersive installations and live performances at International Biennial of Contemporary Art, Venezuela, 9th Korea Experimental Arts Festival, Seoul, Happy New Ears Festival, Belgium, Q-02, Belgium, Ear to the Earth Festival, Judson Church and The Stone.